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Third Harmonic Bio
Cambridge, MA, United States
About Third Harmonic Bio Third Harmonic Bio is a biopharmaceutical company with a singular purpose: To create a breakthrough treatment for people living with severe allergy and inflammation - debilitating conditions that can take a significant toll on overall health and well-being. We are developing a highly selective oral wild-type KIT inhibitor
Job Source: Third Harmonic BioNovo Nordisk
Lexington, MA, United States
About the Department Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the
Job Source: Novo NordiskKestrel Therapeutics
Boston, MA, United States
Associate Director/Director, Medicinal Chemistry At Kestrel our aspiration is to invent brilliant technologies and develop novel small molecule agents for cancer targets of exceptional scientific and clinical import, beginning with mutant RAS. Our reliance is on the rigorous application of innovative science in the service of the discovery of new
Job Source: Kestrel Therapeutics1910genetics
Boston, MA, United States
Director/Senior Director of Medicinal Chemistry Computation is revolutionizing drug discovery. Advances in bigchemical data, massive computing power, artificial intelligence, andmolecular dynamics simulation are changing the way we develop newdrugs. At 1910 Genetics, we put computation at the heart of drugdiscovery, blending expertise in c
Job Source: 1910genetics1910genetics
Boston, MA, United States
Computation is revolutionizing drug discovery. Advances in bigchemical data, massive computing power, artificial intelligence, andmolecular dynamics simulation are changing the way we develop newdrugs. At 1910 Genetics, we put computation at the heart of drugdiscovery, blending expertise in computational chemistry, structuralbiology, pharmacology,
Job Source: 1910geneticsNovartis Farmacéutica
Cambridge, MA, United States
Senior Principal Scientist, Computational Medicinal Chemistry Job ID 390639BR Jan 23, 2024 USA About the Role Internal Role Title: AD and Senior Principal Scientist, Data Science Location: Cambridge, MA About this role: Join our vibrant and innovative Computer-Aided Drug Discovery (CADD) team in Cambridge, where we bring together diverse t
Job Source: Novartis FarmacéuticaNovartis Group Companies
Cambridge, MA, United States
390639BR Senior Principal Scientist, Computational Medicinal Chemistry USA About the role Internal Role Title: AD and Senior Principal Scientist, Data Science Location: Cambridge, MA About this role: Join our vibrant and innovative Computer-Aided Drug Discovery (CADD) team in Cambridge, where we bring together diverse talents to redefine th
Job Source: Novartis Group Companies1910genetics
Boston, MA, United States
Computation is revolutionizing drug discovery. Advances in bigchemical data, massive computing power, artificial intelligence, andmolecular dynamics simulation are changing the way we develop newdrugs. At 1910 Genetics, we put computation at the heart of drugdiscovery, blending expertise in computational chemistry, structuralbiology, pharmacology,
Job Source: 1910geneticsBoston, MA, United States
Computation is revolutionizing drug discovery. Advances in bigchemical data, massive computing power, artificial intelligence, andmolecular dynamics simulation are changing the way we develop newdrugs. At 1910 Genetics, we put computation at the heart of drugdiscovery, blending expertise in computational chemistry, structuralbiology, pharmacology, genetics, data science, and softwareengineering to develop drugs for previously undruggable targets.
You are someone we can count on to... Act as both an Individual Contributor (IC), who can roll up her sleeve, and play an important role in our mission to use AI/ML to develop drugs against historically difficult disease targets, as well as a Leader who can build and grow the Medicinal Chemistry team
You will own... All aspects of the company’s medicinal chemistry efforts across therapeutic modalities, disease targets, and indications
Effective collaboration with computational chemists in virtual screening campaigns to rapidly identify drug candidates for further development
Effective collaboration with the ML Engineering and AI Research team by providing key medicinal chemistry insights to aid in the development of AI/ML models for drug discovery
The growth of the Medicinal Chemistry team over time
You will teach... Key medicinal chemistry principles to your cross-disciplinary colleagues from Computational Chemistry, AI Research, Machine Learning Engineering, Cell Biology, and Pharmacology
You will learn... AI/ML applied to drug discovery
You will improve... Our existing process of progressing from computational hit to experimental hit to lead to drug candidate
Within 1 month you will... Nominate a few hundred virtual hits for synthesis
Within 3 months you will... Progress a virtual hit to a biochemical/cellular hit
Author provisional patents on hit scaffolds
Within 6 months you will... Validate a cellular hit in a clinically relevant animal model of disease
Update provisional patents with the animal model data
Within 12 months you will... Nominate a lead candidate for progression into IND-enabling studies
Grow the Medicinal Chemistry team
This is an exciting time to join a fast growing startup on a mission to save human lives. If you enjoy working on important problems with a small team of passionate and fun individuals, come join us!
Extremely generous equity package coupled with competitive salary
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Email Alert for Lead, Medicinal Chemistry jobs in Boston, MA, United States
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