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Rezotx
San Francisco, CA, United States
Scientist II/Senior Scientist, Discovery Sciences About Rezo Therapeutics Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat
Job Source: RezotxScorpion Therapeutics
San Francisco, CA, United States
Scorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platform of the most advanced technologies across cancer biology, medicinal chemistry, and da
Job Source: Scorpion TherapeuticsScorpion Therapeutics, Inc.
San Francisco, CA, United States
ScientistI/Scientist II, Biology (Must Have Small Molecule Drug Discovery Experience) Scorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platfo
Job Source: Scorpion Therapeutics, Inc.Nurix Therapeutics
San Francisco, CA, United States
Position We are seeking a highly skilled and motivated immunologist to support Nurix's mission of targeting E3 ubiquitin ligases in the areas of immunology and oncology. This individual will work closely with our drug discovery project teams on optimization and characterization of novel compounds to evaluate their impact on immune cells and diseas
Job Source: Nurix TherapeuticsThe Chan Zuckerberg Biohub, Inc.
San Francisco, CA, United States
The Opportunity The CZ Biohub SF brings together scientists and engineers striving to understand the inner workings of complex cellular systems. We build large, open datasets that map cellular architecture across scales, including atlases that define human sub-cellular organization ( https://opencell.czbiohub.org/ ), mammalian cell types ( https:/
Job Source: The Chan Zuckerberg Biohub, Inc.Confidential
South San Francisco, CA, United States
Vice President Biology, Microglial Expert About the Company Innovative biopharmaceutical company Industry Pharmaceuticals Type Public Company Founded 2013 Employees 201-500 Categories Pharmaceuticals Biotechnology Health Care Medical Conditions Medicines Clinical Care Academic Research Medicine Manufacturing Chemical Products About the Role The C
Job Source: ConfidentialFirefly Bio
San Francisco, CA, United States
About Firefly Bio: Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. Our mission is to unlock the full potential of bioconjugates and develop medicines with long-lasting benefits for patients. We are establishing an expert team to build state-of-the-art platform
Job Source: Firefly BioArcadia Science LLC
Berkeley, CA, United States
A Bit About Us: We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into real-world solutions by openly developing more efficient, replicable, and sustainable ways to leverage the biology of diverse organisms. We expect scientists at Arcadia to openly publish their
Job Source: Arcadia Science LLCAlameda, CA, United States
Scribe Therapeutics is a molecular engineering company focused on creating best-in-class in vivo therapies that permanently treat the underlying cause of disease. Founded by CRISPR inventors and leading molecular engineers Benjamin Oakes, Brett Staahl, David Savage, and Jennifer Doudna, Scribe is overcoming the limitations of current genome editing technologies by developing custom engineered enzymes and delivery modalities as part of a proprietary, evergreen CRISPR by Design platform for CRISPR-based genetic medicine.
We are seeking a highly creative, passionate, and motivated individual to join us in our quest to develop the next generation of CRISPR-based therapeutics. The current role is for a Scientist to join our team and advance our platform. The candidate should have a passion for working collaboratively with biologists and bioengineers to enable building the necessary tools for meeting the new frontier of CRISPR-based therapeutics. Additionally, the candidate would bring expertise in genetic medicine for neurodegenerative/muscular diseases, as well as upstream R&D processes to lead screening and therapeutic discovery efforts.
The candidate will have numerous opportunities for professional growth in a rapidly growing biotechnology start-up, which includes growing into a leadership role of increasing responsibilities and the ability to publish highly impactful work in peer reviewed journals.
Key Responsibilities:
As part of a 2-3 member team focused on specific disease targets, you will:
Collaborate cross-functionally to execute early-stage discovery research pipeline assets for neurodegenerative diseases.
Develop, characterize, and execute novel molecular and cell-based assays to support screening and preclinical development.
Communicate scientific progress effectively to stakeholders and facilitate project execution within established timelines.
Generate, manage, evaluate, and maintain critical data in an organized manner, providing statistical analysis and troubleshooting as needed.
Cultivate a driven, dynamic, and enjoyable environment for rigorous scientific inquiry.
Required Skills and Background:
PhD in Molecular and Cell Biology, Genomics, Stem Cells, Bioengineering, or equivalent, with a minimum of 2 years of working experience.
Deep knowledge of early-stage discovery research for gene therapies applied to CNS/neuromuscular diseases.
Extensive experience in developing cell-based assays using primary cells, with additional experience in working with primary neurons and other iPSC-derived CNS cell types preferred.
Proficiency in common hands-on techniques in molecular biology and imaging (cloning, ELISA, RT PCR-qPCR, IHC/ICC, confocal imaging).
Experience with in vitro pharmacology and quantitative methods.
Strong experimental design and problem-solving skills, demonstrated by a publication record.
Ability to work independently and collaboratively in a fast-paced, interdisciplinary research team.
Preferred Skills and Background:
Industry experience is highly desirable.
Familiarity with CRISPR technologies.
Prior experience with diverse delivery technologies, including transfection/nucleofection, lipid nanoparticles, and viral vectors/particles.
Salary will be commensurate with experience. We will provide an intellectually stimulating, collegial and fast-paced environment. If you are ready to engineer the future of therapeutics, then we are excited to hear from you! Visit us at www.scribetx.com .
We are committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, disability, age, or veteran status.
At the time of posting, the base pay wage range for this role is $100,000-130,000per year. The offered pay range will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data. Additional incentives are provided as part of the complete package in addition to comprehensive medical and other benefits.
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Email Alert for Scientist I/II, Discovery Biology CNS jobs in Alameda, CA, United States
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