Scientist, Process Chemistry

Boston, MA, United States

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Scientist, Process Chemistry where you will be responsible for the invention and development of drug substance manufacturing processes, with a focus on biocatalytic processes, to advance Takeda's pipeline of synthetic small molecules. You will also identify, resource, develop, transfer, and integrate biocatalysis processes promptly within our development asset processes thereby improving quality, safety, cost, and sustainability metrics. As part of the Synthetic Molecule Process Development (SMPD), you will report to Associate Director, Process Chemistry Development and work within a matrix environment of process development chemists and engineers investigating biocatalytic transformations.

How you will contribute:

Invent and develop safe, reproducible, and cost-effective processes to manufacture synthetic small molecules.

Contribute to biocatalysis projects through independent research, in addition to leading or influencing others in a matrix environment.

Prepare and coordinate the completion of technical documentation, regulatory documents, validation plans, and reports.

Coordinate the transfer of projects, ensuring smooth transitions and maintaining project quality.

Stay updated on emerging trends and advancements in organic chemistry, process development, and biocatalysis. Identify opportunities for continuous improvement for biocatalytic techniques, processes, and systems.

Work cross-functionally to ensure continued innovation for SMPD.

Contribute significantly to develop, drive, and set vision and direction of departmental scientific and strategic initiatives.

Identify topics for initiatives and lead local/global initiatives on behalf of senior staff.

Contribute to complex/multiple projects or functional areas through leading or influencing others.

Influence and support initiatives related to driving scientific and technical improvement within function and potentially cross-functionally.

Ensure a productive and development-rich environment.

Define more complex/novel approaches and methodologies to solving complex technical challenges.

Proactively identify vendors and build relationships to gain access to technologies as needed to deliver on pipeline goals.

Understand project timelines and deliverables and plan/coordinates project work accordingly with departmental, functional, and external stakeholders.

Provide technical leadership to project teams within area of expertise.

Contribute significantly and independently to project work which may include multiple projects within functional area.

Review, interpret and communicate data cross-functionally within CMC and project teams.

Plan and implement resolutions to technical problems/issues.

Independently design and execute experiments, and reports results.

Responsible for integrating scientific/technical efforts around cross-functional issues.

Minimum Requirements/Qualifications:

A Ph.D. degree with 0+ years pharmaceutical industry experience; an MS degree with 6+ years of relevant pharmaceutical industry experience; or a BS degree with 8+ years of relevant pharmaceutical industry experience.

Bachelors or Masters: Extensive experience in CMC pharmaceutical development for active pharmaceutical ingredients and drug products under cGMP's; sound knowledge of current Good Manufacturing Practices (cGMP); previous experience with the use of contract facilities

Experience working in a multi-disciplinary team environment.

PhD: Demonstrated mastery of subject or area related to field; Extensive experience in synthetic organic chemistry and route design for synthetic molecule construction.

Experience developing biocatalytic transformations is preferred.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$108,500.00 - $170,500.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

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