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Yoh Services LLC
South San Francisco, CA, United States
Yoh is hiring a Sr. Staff Scientist/Associate Director - Disease Biology & Translational Sciences for our S. San Francisco, CA client. In this role , will be responsible for helping to establish and expand the company’s capabilities for preclinical in vitro and clinical ex vivo disease pathobiology establishing in vitro/ex vivo models to inter
Job Source: Yoh Services LLCGreenstonebio
Palo Alto, CA, United States
We operate at the convergence and cutting-edge of science and technology. Join us and our rapidly growing team of computational biologists and life scientists who are dedicated to transforming how we discover treatments for patients in need. Artificial Intelligence Scientist - Drug Discovery Greenstone Biosciences is a health care company that is
Job Source: GreenstonebioReCode Therapeutics, Inc.
Menlo Park, CA, United States
Summary of Position: We are seeking an accomplished and detail-oriented scientist dedicated to establishing robust in vitro models and primary airway cell cultures for the research and evaluation of ReCode’s therapeutics. While the majority of this role will be hands-on benchwork, people leadership responsibilities may be included based on experie
Job Source: ReCode Therapeutics, Inc.Alector, Inc.
South San Francisco, CA, United States
Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare in
Job Source: Alector, Inc.Earli
Redwood City, CA, United States
About Earli Earli exists to make cancer a benign experience. Earli does that by turning cancers against themselves: genetically forcing them to reveal themselves early, and then kill themselves - precisely and clearly distinguishable from benign lesions at early stages. Based on original technology from Stanford's renowned Gambhir lab, Earli design
Job Source: EarliLongevitylist
San Carlos, CA, United States
Arda is targeting cells to treat disease. We are taking aim at chronic diseases and aging by eliminating the pathogenic cells that drive these conditions. A new approach to old diseases Cells are the functional units of life, but they are also the functional units of disease. Many diseases are caused by certain cell populations becoming too abundan
Job Source: LongevitylistMeet Recruitment Limited
Newark, CA, United States
Job Title: VP, Biology We are seeking an entrepreneurial, strategic, and visionary scientific leader to join our client’s team as the VP of Biology. Reporting directly to the EVP, Chief Drug Discovery and Pre-clinical Development Officer, this critical role is part of the R&D Leadership Team. The successful candidate will be instrumental in buildin
Job Source: Meet Recruitment LimitedGilead Sciences, Inc.
Foster City, CA, United States
Senior Research Scientist I, DMPK page is loaded Senior Research Scientist I, DMPK Bewerben locations United States - California - Foster City time type Full time posted on Vor 5 Tagen ausgeschrieben job requisition id R0040942 For Current Gilead Employees and Contractors:
Job Source: Gilead Sciences, Inc.Redwood City, CA, United States
Senior Research Associate / Scientist, In vitro Drug Discovery We are seeking a talented Senior Research Associate / Scientist to be an integral part of our drug discovery platform expansion to include disease model systems for emerging projects. We are searching for an individual who is excited to develop in vitro disease model systems in an intimate and small team focused on the discovery, preclinical validation, and clinical translation of novel biologics for chronic and rare degenerative diseases. The individual will be an integral member of the expanding discovery team to increase our pipeline of state-of-the-art biologics. The ideal candidate will have industry experience in a drug discovery and early development setting and have been involved in high throughput screening, lead candidate selection, and IND-enabling studies for biologics.
Company Summary
Juvena Therapeutics is on a mission to discover and develop biologics for rare and chronic degenerative diseases by mining the secretomes of human pluripotent stem cells through a machine learning (ML)-enhanced platform. Juvena’s approach integrates proteomics, transcriptomics and imaging with phenotypic human in vitro disease model screening and extensive preclinical validation to mine stem cell secretomes as a rich source of new medicines for chronic and rare diseases. We are advancing leads for muscular dystrophies and muscle atrophy, and validating hits across metabolic and pulmonary diseases with a goal to identify and develop two new assets in new disease indications over the next two years. Since our launch in mid-2018, Juvena has discovered dozens of hits for neuromuscular, skeletal, metabolic and pulmonary diseases, including several muscle regenerative protein therapeutic candidates with potent human in vitro and mice in vivo efficacy. Juvena is advancing a developmental candidate for Myotonic Dystrophy Type 1, a rare autosomal dominant, progressive muscle-wasting disease, in IND-enabling studies.
Juvena Therapeutics has secured venture capital, NIH, and CIRM funding to develop our top lead to a clinical-stage investigational new drug, to build our stem cell secretome database, and to leverage our discovery platform to rapidly identify and validate novel protein-based drug candidates for multiple rare and chronic diseases across metabolic and pulmonary therapeutic areas. At Juvena we embrace a diversity of backgrounds, experience and approaches that all combine to lead us to world-class scientific results in an inclusive environment.
Major Responsibilities
Build our expertise in human disease models to expand Juvena’s platform screening capabilities across multiple organ model systems
Integrate the latest in cell culture techniques and analytical methods to increase throughput and information content in our in vitro screening and pharmacology
Oversee and perform experiments in disease model systems as well as support our projects with cell-based and biochemical assays
Communicate scientific data internally and externally
Contribute to a dynamic and exciting culture that embraces teamwork and innovation
Maintain flexibility in supporting multiple discovery and preclinical projects as the company grows
Position Requirements and Experience
A relevant Ph.D. degree in biochemistry, cell biology, or a related field with 2-5 years of industry experience in a drug discovery environment
Demonstrated ability to support small molecule or biologic-based high-throughput screening projects
Documented experience with assay development and troubleshooting
Preferred Qualifications
Experience with 3D cell cultures or organoids
Experience with high content imaging, automation, or NGS pipelines
Knowledge of regenerative medicine, cardiometabolic, and pulmonary disease areas
Understanding of how disease model data fits into bioinformatics and machine learning applications
Compensation and Benefits
Competitive salary and annual bonus and stock options
Paid vacation and holidays
More benefits coming soon (including initiation of 401(k) matching program)
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Email Alert for Senior Research Associate / Scientist, In vitro Drug Discovery jobs in Redwood City, CA, United States
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