Senior Scientist / Principal Scientist, Cell Biology – Lung Epithelia
Menlo Park, CA, United States
Summary of Position:
We are seeking an accomplished and detail-oriented scientist dedicated to establishing robust in vitro models and primary airway cell cultures for the research and evaluation of ReCode’s therapeutics. While the majority of this role will be hands-on benchwork, people leadership responsibilities may be included based on experience of the candidate.
The candidate is expected to be a subject matter expert in mucosal biology of the lung. Work experience or publications in respiratory diseases, such as CF, PCD, IPF, or ARDS, would be highly regarded. He/she will support a team of research scientists and research associates developing therapeutics for lung diseases with ReCode’s proprietary lipid nanoparticle (LNP) delivery vehicle solutions. The qualified candidate is a highly motivated, interactive, and team-oriented individual who can work across a matrixed environment.
This is a unique opportunity to be part of a fast-paced, rapidly growing company developing a pipeline of therapies for severe life-limiting diseases.
Responsibilities:
Subject matter expert in lung mucosal biology and primary human cell culture models.
Design, oversee and/or execute cell biology experiments, applying advanced molecular techniques and assays in a therapeutic drug discovery workflow.
Oversee the design and execution disease-relevant assays across diverse therapeutic applications internally and through CRO partners.
Ensure site-wide electronic lab notebook and record keeping complies with company policies.
Contribute to the discovery and early preclinical research plans, including defining key milestones and decision points and timelines, identifying risks and mitigation strategies towards later development and IND filings.
Qualifications:
PhD in molecular biology, cell biology or related discipline with typically 5-8+ years of experience in industry (exact level and title will be commensurate with experience)
Expertise in primary human airway derived cell culture systems.
Prior experience and willingness to work in a BSL2 environment.
Prior working knowledge of Molecular Biology Assays (e.g. Western blot, qPCR, NGS etc.), Cell Biology Assays (e.g. immunofluorescence, cell imaging and microscopy etc.) and Functional Biology (e.g. Ussing chambers, etc.)
Experience with non-viral delivery platforms preferred but not required.
Advanced knowledge of statistical tools (Microsoft Excel, GraphPad, RStudio)
Ability to communicate complicated scientific concepts to a diverse audience.
Position is based in Menlo Park, CA and the expectation is for full on-site presence.
Salary Range:
Senior Scientist I: 145-155K
Senior Scientist II: 160-170K
Principal Scientist: 175-185K
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