Email Alert for
ⓘ There was an unexpected error processing your request.
Please refresh the page and try again.
If the problem persists, please contact us with your issue.
You can always manage your preferences and update your interests to ensure you receive the most relevant opportunities.
Get ready to discover your next great opportunity.
Bristol Myers Squibb
Brisbane
**Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that tra
Job Source: Bristol Myers SquibbNurix Therapeutics
San Francisco, CA, United States
Nurix Therapeutics () is a private biopharmaceutical company developing novel small molecule immune modulators for the treatment of cancer and autoimmune diseases. Based on the successful progress of our R&D platform, including expertise in medicinal chemistry, immune cell biology and in vivo pharmacology, Nurix is advancing multiple programs to th
Job Source: Nurix TherapeuticsNurix
San Francisco, CA, United States
Nurix Therapeutics (www.nurixtx.com) is a private biopharmaceutical company developing novel small molecule immune modulators for the treatment of cancer and autoimmune diseases. Based on the successful progress of our R&D platform, including expertise in medicinal chemistry, immune cell biology and in vivo pharmacology, Nurix is advancing multiple
Job Source: NurixEquilibrium Energy
San Francisco, CA, United States
What we are looking for Equilibrium was founded with a vision for building a company where innovation, collaboration, optimization, machine learning, and data science power all aspects of our algorithmic decision-making. We are looking for a staff / sr staff research scientist with deep power markets domain expertise to accelerate the design a
Job Source: Equilibrium EnergyTrc Companies, Inc.
San Francisco, CA, United States
About Us Groundbreaker. Game changer. Pioneer. TRC has long set the bar for clients who require more than just engineering, combining science with the latest technology to devise innovative solutions that stand the test of time. From pipelines to power plants, roadways to reservoirs, schoolyards to security solutions, clients look to TRC for break
Job Source: Trc Companies, Inc.Equilibrium Energy
San Francisco, CA, United States
What we are looking for Equilibrium was founded with a vision for building a company where innovation, collaboration, machine learning, and data science power all aspects of our algorithmic decision-making. We are looking for staff / sr staff machine learning scientists to accelerate the design and delivery of our machine learning models,
Job Source: Equilibrium EnergySan Francisco, CA, United States
About Pinterest : Millions of people across the world come to Pinterest to find new ideas every day. It's where they get inspiration, dream about new possibilities and plan for what matters most. Our mission is to help those people find their inspiration and create a life they love.In your role, you'll be challenged to take on work that upholds t
Job Source: PinterestEquilibrium Energy
San Francisco, CA, United States
About our Company Equilibrium Energy is a well-funded, Series B clean energy startup backed by some of the most prominent institutional investors in climate. We are building a digital native power company operating at the intersection of grid variability, market volatility, economic optimization, commercial structuring, and risk management, across
Job Source: Equilibrium EnergySouth San Francisco, CA, United States
Yoh is hiring a Sr. Staff Scientist/Associate Director - Disease Biology & Translational Sciences for our S. San Francisco, CA client. In this role , will be responsible for helping to establish and expand the company’s capabilities for preclinical in vitro and clinical ex vivo disease pathobiology establishing in vitro/ex vivo models to interrogate complex disease models to rank and screen our therapeutic candidates and establish the drug’s mechanism of action for multiple indications. You will lead cell based therapeutic characterization and development efforts defining the compounds mechanism of action and efficacy in complex in vitro models of disease. You will lead from the bench managing internal scientists as well as external CROs to execute strategies and be responsible for the development and conduct of in vitro , and/or ex vivo studies to support and advance company's drug discovery pipeline. You will establish pharmacodynamic and efficacy relationships as appropriate to determine the potential clinical impact of company's drugs. You will serve as the Disease Biology lead on cross-functional research and development teams and have opportunities to lead programs from discovery through early development.
Industry : Drug Discovery
Location : S. San Francisco, CA
Compensation : $175k - $200k (based upon experience)
Type : Direct Hire
Key Responsibilities
Design and execute in vitro and ex vivo studies to advance therapeutic programs
Generate, analyze, and interpret complex data to establish functional PK/PD and efficacy relationships and elucidate therapeutic mechanism of action for leads drugs
Serve as Disease Biology lead on multiple project teams, conduct and trouble-shoot experiments, analyze and interpret data and work cross functionally with colleagues to identify and mitigate risks and effectively advance therapeutic programs
Help build complex in vitro and ex vivo research and development capabilities
Author and review protocols, study reports, and regulatory documents to enable IND and other regulatory filings
Yoh is hiring a Sr. Staff Scientist/Associate Director - Disease Biology & Translational Sciences for our S. San Francisco, CA client. In this role , will be responsible for helping to establish and expand the company’s capabilities for preclinical in vitro and clinical ex vivo disease pathobiology establishing in vitro/ex vivo models to interrogate complex disease models to rank and screen our therapeutic candidates and establish the drug’s mechanism of action for multiple indications. You will lead cell based therapeutic characterization and development efforts defining the compounds mechanism of action and efficacy in complex in vitro models of disease. You will lead from the bench managing internal scientists as well as external CROs to execute strategies and be responsible for the development and conduct of in vitro , and/or ex vivo studies to support and advance company's drug discovery pipeline. You will establish pharmacodynamic and efficacy relationships as appropriate to determine the potential clinical impact of company's drugs. You will serve as the Disease Biology lead on cross-functional research and development teams and have opportunities to lead programs from discovery through early development.
Industry : Drug Discovery
Location : S. San Francisco, CA
Compensation : $175k - $200k (based upon experience)
Type : Direct Hire
Key Responsibilities
Design and execute in vitro and ex vivo studies to advance therapeutic programs
Generate, analyze, and interpret complex data to establish functional PK/PD and efficacy relationships and elucidate therapeutic mechanism of action for leads drugs
Serve as Disease Biology lead on multiple project teams, conduct and trouble-shoot experiments, analyze and interpret data and work cross functionally with colleagues to identify and mitigate risks and effectively advance therapeutic programs
Help build complex in vitro and ex vivo research and development capabilities
Author and review protocols, study reports, and regulatory documents to enable IND and other regulatory filings
Education, Skills & Experience PhD Endocrinology, Physiology, Diabetes/Obesity, Immunology / Inflammation, or Metabolic Disease, or related biological science (MSc/BSs with relevant years of experience)
At least 8 years direct hands-on experience in therapeutic development leveraging indication specific functional disease models in biotechnology and pharmaceutical industries (MSc with at least 12years, BSc with at least 14years)
MUST have experience with therapeutics programs which have yielded drugs entering clinical development in diabetes or obesity
Experience with cell-based assays, ELISA, MSD, qPCR, RNA-seq, microscopy, histology/pathology (e.g. IF/IHC/ISH), and/or flowcytometry
Ability to be hands on and working in the lab, manage scientists, write protocols, execute studies leveraging company's in house capabilities or working with CROs
Direct experimental experience with complex disease biology of diabetes, obesity or other metabolic disease
Demonstrated expertise in building PK/PD and efficacy relationships with complex 2D/3D functional cell-based and tissue-based assays
Leverage complex data sets to characterize therapeutic leads and establish a drug’s therapeutic mechanisms of action
Experience working on/leading project teams with functional responsibility to propose strategy, analyze, interpret, and present complex data to inform decisions
Ability to collaborate in writing protocols, reports, and regulatory documents
Experience working with vendors and CROs to execute studies, analyze data, and generate reports in a timely manner
Experience authoring study protocols, reports, and/or regulatory documents including IBs, IND filings, CSRs, and/or NDAs
Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Visit https://www.yoh.com/applicants-with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.
#J-18808-Ljbffr
Email Alert for Sr. Staff Scientist/Associate Director jobs in South San Francisco, CA, United States
ⓘ There was an unexpected error processing your request.
Please refresh the page and try again.
If the problem persists, please contact us with your issue.
You can always manage your preferences and update your interests to ensure you receive the most relevant opportunities.
Get ready to discover your next great opportunity.