Email Alert for
ⓘ There was an unexpected error processing your request.
Please refresh the page and try again.
If the problem persists, please contact us with your issue.
You can always manage your preferences and update your interests to ensure you receive the most relevant opportunities.
Get ready to discover your next great opportunity.
Deciduoustx
San Francisco, CA, United States
Deciduous Therapeutics is an early stage, venture backed biotechnology company based in San Francisco, CA. Our mission is to develop novel drugs that activate the endogenous immune system to eliminate senescent cells for the treatment of age-related diseases in the fibrosis and metabolic therapeutic areas. We are looking for a highly ambitious Scie
Job Source: DeciduoustxNurix
San Francisco, CA, United States
Position We are seeking a highly skilled and motivated immunologist to support Nurix's mission of targeting E3 ubiquitin ligases in the areas of immunology and oncology. This individual will work closely with our drug discovery project teams on optimization and characterization of novel compounds to evaluate their impact on immune cells and diseas
Job Source: NurixShennonbio
San Francisco, CA, United States
We are a well-funded biotech startup in San Francisco that has developed a proprietary single cell platform that resolves a bottleneck for immunotherapy. We are utilizing the platform to develop the next generation of immunotherapies that could cure cancer. We are looking to double the current size of our team and are actively hiring for many posit
Job Source: ShennonbioNurix Therapeutics
San Francisco, CA, United States
Position We are seeking a highly skilled and motivated immunologist to support Nurix's mission of targeting E3 ubiquitin ligases in the areas of immunology and oncology. This individual will work closely with our drug discovery project teams on optimization and characterization of novel compounds to evaluate their impact on immune cells and diseas
Job Source: Nurix TherapeuticsGenentech
South San Francisco, CA, United States
The Position A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. Recently, exciting developments at Genentech and elsewhere
Job Source: GenentechEnvivo
San Francisco, CA, United States
At Envivo Bio, we are looking for people from a wide variety of backgrounds and experiences who can challenge assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national or
Job Source: EnvivoGenentech
South San Francisco, CA, United States
The Position The Position A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. Genentech seeks a talented and highly motiva
Job Source: GenentechAmazon
San Francisco, CA, United States
Job ID: 2593405 | Amazon Development Center U.S., Inc. At AWS, we build and operate AI services responsibly, driving measurable success along multiple Responsible AI dimensions, including safety, fairness, privacy, security, robustness, explainability, and transparency. As a Principal Applied Scientist on this team, you will contribute to: • Unde
Job Source: AmazonSan Francisco, CA, United States
Site Therapeutics aims to map—down to the nucleotide—the genetic determinants driving immune cell function in human health and disease and to use that information to develop first-in-class small molecule therapeutics for autoimmune disease. Leveraging technology developed in the Marson Lab at UCSF/Gladstone, we will conduct high-throughput functional genomics in human cells to build a blueprint for fine-tuned control of immune cell function. This detailed map will lead to the development of new therapeutics across modalities for a range of immune-related conditions. We are backed by The Column Group, a leading life sciences venture capital firm.
We are seeking passionate scientists and research associates of all levels with a strong interest in adaptive immunology and functional genomics to join our launch team. Our Principal Scientist, Immunology position will be a part of a team leading efforts to systematically map residues governing disease-relevant phenotypes.
The primary responsibilities of the Principal Scientist, Immunology will be:
Prioritization of screening phenotypes in primary immune cells with therapeutic translatability to human autoimmune disease
Development of immunological, biological and biochemical assays to screen and validate novel targets and their associated mechanisms
Optimization of primary human T cell and other lymphocyte or myeloid culture
Flow cytometry and fluorescence-activated cell sorting (FACS) of primary human cells
Design and optimization of high-throughput base editing screens to identify sites on proteins with functional consequences in autoimmune relevant phenotypes
Development of novel protocols and standard operating procedures (SOPs) associated with culturing, differentiating, and screening primary human immune cells
Close collaboration with a team of Scientists and Research Associates to stick to tight timelines while creating a large map of genomic sites impacting immune cells
Stay up-to-date with emerging scientific literature and share your ideas liberally
Strong organizational and communication skills are required. This position represents a unique opportunity to lead cutting-edge genetic editing research at the frontier of human immunology and to have an outsized impact on success in the dynamic, rapidly evolving research environment of an early stage startup.
Qualifications:
Ph.D. in immunology or related field, and 5-10 years of laboratory (industrial or postdoctoral) experience
Experience with immunological assay development and flow cytometry and/or FACS, high-throughput preferred
Experience uncovering new mechanisms of action for known immunology-associated targets and/or validating mechanisms of action for novel immunology-associated targets
Experience with mammalian cell culture, primary cells preferred
Excellent organizational and interpersonal communication skills (verbal and written)
Willingness and ability to learn new methods and skills for changing research priorities
Evidence of scientific excellence and impact as illustrated by scientific publications and presentations
Ability to keep detailed and organized records of experimental protocols and results
Ability to work independently and as a member of a research team
Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines
Self-starter with an interest in building a team from the ground up at a brand new start-up
We offer:
In addition to a competitive compensation package with stock options, we offer comprehensive health, dental, and vision benefits for employees and their families.
We believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws.
#J-18808-Ljbffr
Email Alert for Principal Scientist, Immunology jobs in San Francisco, CA, United States
ⓘ There was an unexpected error processing your request.
Please refresh the page and try again.
If the problem persists, please contact us with your issue.
You can always manage your preferences and update your interests to ensure you receive the most relevant opportunities.
Get ready to discover your next great opportunity.