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Altos Labs
San Francisco, CA, United States
Our Mission Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos We believe that
Job Source: Altos LabsMedium Biosciences
San Francisco, CA, United States
About you We are seeking a passionate, self-motivated scientist excited about protein design and the development of our platform. You will work with the team to design and validate assays for high-throughput multiplexed protein characterization starting with binding. You will be a part of founding team charting new path for how we design proteins
Job Source: Medium BiosciencesApertor Pharmaceuticals
Alameda, CA, United States
Apertor Pharmaceuticals Inc. was founded in November 2020 and will bring new therapies to patients by engineering molecular glues using synthetic biology. We apply a world-class synthetic biology platform using non-model organisms, a deep knowledge of natural products relevant to human health, and a computational pipeline enabled by structure-guide
Job Source: Apertor PharmaceuticalsFrontier Medicines
South San Francisco
Frontier Medicines is seeking a highly motivated individual to fill the position of Scientist / Senior Scientist, Disease Biology to join our South San Francisco team that is focused on target validation, drug mechanism of action and resistance, cancer biology, pharmacology, and biomarker discovery. The successful candidate will play a leading role
Job Source: Frontier MedicinesAltos Labs
San Francisco, CA, United States
Our Mission To restore cell health and resilience through cellular rejuvenation programming to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos We believe tha
Job Source: Altos LabsThe Cell Company (CellCo)
San Francisco, CA, United States
At CellCo, we are at the forefront of merging synthetic biology with AI to decode the complexity of mammalian systems and generate breakthrough therapeutics. We leverage cutting-edge technology to program novel molecular circuits, including cell and cell-free approaches, while incorporating biomimicry—learning from nature’s own strategies. We are c
Job Source: The Cell Company (CellCo)California Life Company
San Francisco, CA, United States
Who We Are: Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier live
Job Source: California Life CompanyUniversity of California - San Francisco
San Francisco, CA, United States
Application Window Open date: January 31, 2024 Next review date: Thursday, Feb 15, 2024 at 11:59pm (Pacific Time) Apply by this date to ensure full consideration by the committee. Final date: Thursday, Jul 31, 2025 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review dat
Job Source: University of California - San FranciscoSan Francisco, CA, United States
Job Description
KP Recruiting Group is a consulting firm that provides leadership and exceptional talent to some of the world's leading companies. Headquartered in the Midwest, KP Recruiting Group has successfully completed countless engagements across the United States. We represent clients in all industries and all sizes. Our mission is to provide exceptional client and candidate experiences in order to get the best possible results. On behalf of our client, we are excited to present the following confidential role. We look forward to hearing from you and discussing the opportunity!
The Role:
Our client's Musculoskeletal Therapeutic Area is seeking a highly motivated Scientist I or II to join the team. We are professional scientists with a passion for making therapeutics that have a big impact on lives and are devoted to sharing scientific findings with the community. We value kindness and generosity in the workplace, a healthy work/life balance and emphasize mentorship and the growth and support of our colleagues.
The successful candidate will be responsible for the intellectual and hands on evaluation of therapeutic strategies in support of the research pipeline. In the act of doing so, they will have multidisciplinary interactions with dozens of colleagues throughout Research and across the business. This is primarily a laboratory-based role where in vitro molecular, cellular, genetic and biochemical methods will be applied.
The successful candidate has:
A passion for finding treatments for rare genetic diseases.
A strong foundation in molecular, cellular, genetic, and biochemical concepts and methodology as demonstrated through publications and presentations.
Demonstrable success in:
Designing and carrying out lean sets of experiments that produce actionable data; proposing hypotheses, testing them, and delivering reliable results consistently.
Rapidly mastering new fields and methods and connecting with KOLs.
Presenting experimental results, conclusions, implications, and next steps.
Meticulously adhering to electronic data recording standards.
Collaborating and working in teams.
Incorporating guidance into project strategies.
Knowing the limits of their bandwidth or knowledge and seeking the right help.
Taking initiative and being resourceful.
Composing clear and impactful written and verbal communications.
Working with urgency and efficiency.
Leadership and mentorship.
Receiving and giving feedback with grace.
Automating workflows.
Being a tidy and considerate lab citizen.
Requirements
Required Skills: An expert level ability to develop & conduct the following methods, and to analyze, present, and quickly iterate upon the data generated:
Protein quantification: ELISA, Western/WES or other, and a conceptual understanding of LCMS.
mRNA/DNA quantification: qPCR, ddPCR, knowledgeable of NGS approaches, prep and analysis.
Microscopy: Confocal or other with a breadth of knowledge in sample preparation and image analysis to visualize and quantify cellular events.
Deep experience in cell culture approaches: Knowledgeable on cell lines to use for various applications and Flow cytometry or FACS; has applied transfection and transduction approaches, gene editing, and generated edited or transgenic cell lines.
Modern and traditional molecular cloning approaches (Gibson, etc).
Extra consideration will go to candidates with the following skills/experience:
Expertise or knowledge in skeletal or muscle biology and/or disease such as muscular dystrophy and achondroplasia.
Liquid handling automation and application of other HTS instrumentation.
Experience with therapeutic modality evaluation and/or development: oligonucleotides, small molecules, gene therapy, and/or antibodies.
Differentiation of iPSCs into neurons, cardiomyocytes, or myotubes and methods to evaluate the physiology of those cells.
Functional Genomics: pooled CRISPR screens, etc.
Programming (Python, other).
Benefits
401k Matching
Family and Individual Insurance Packages (Health, Life, Dental, and Vision)
Paid Time Off & Paid Holidays
Long & Short-Term Disability
Identity Theft Plans
Retirement & Pension Plans
Employee Assistance Program
Employee Referral Program
Tuition Reimbursement Programs
Advancement & Professional Growth opportunities
Parental Leave
& More
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Email Alert for Senior Scientist - Cellular Biology and Molecular Genetics jobs in San Francisco, CA, United States
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