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Apogee Therapeutics
Boston, MA, United States
Role Summary The Department of Research and Translational Medicine is seeking a Principal Scientist, Translational Biomarkers. This person will have direct experience in biomarker selection and execution strategies in support of clinical development of programs. This is an on-site position based in the Apogee lab in the Seaport district in Boston
Job Source: Apogee TherapeuticsBirdseye Partners
Waltham, MA, United States
Associate Director (Principal Investigator) – Translational Biomarker (Immunology) We are seeking an experienced translational scientist to lead the design and execution of biomarker strategies supporting our early and late-stage research programs. The candidate will develop translational biomarker approaches that measure target engagement, pharmac
Job Source: Birdseye PartnersNovartis Farmacéutica
Cambridge, MA, United States
Director - Therapeutic Area Biomarker Lead Renal Job ID REQ-10009877 USA Summary #LI-HybridLocation: Cambridge, MAAbout the role:As a Therapeutic Area Biomarker Lead (TABL) for the renal portfolio, you will lead the renal disease area matrix teams of Biomarker Leads (leading at clinical project level) and subject matter experts and support key c
Job Source: Novartis FarmacéuticaNovartis Farmacéutica
Cambridge, MA, United States
Director - Therapeutic Area Biomarker Lead Renal Job ID REQ-10009877 USA Summary #LI-HybridLocation: Cambridge, MAAbout the role:As a Therapeutic Area Biomarker Lead (TABL) for the renal portfolio, you will lead the renal disease area matrix teams of Biomarker Leads (leading at clinical project level) and subject matter experts and support ke
Job Source: Novartis FarmacéuticaNovartis Group Companies
Cambridge, MA, United States
Job Description Summary #LI-Hybrid Location: Cambridge, MA About the role: As a Therapeutic Area Biomarker Lead (TABL) for the renal and/or global health (malaria, leishmaniasis, dengue and Chagas) portfolios, you will lead the renal and global health disease area matrix teams of Biomarker Leads (leading at clinical project level) and subject mat
Job Source: Novartis Group CompaniesHealthcare Businesswomen's Association
Cambridge, MA, United States
Job Description Summary #LI-Hybrid Location: Cambridge, MA About the role: As a Therapeutic Area Biomarker Lead (TABL) for the renal portfolio, you will lead the renal disease area matrix teams of Biomarker Leads (leading at clinical project level) and subject matter experts and support key clinical projects as Biomarker Lead. Biomarkers are crit
Job Source: Healthcare Businesswomen's AssociationBioSpace, Inc.
Boston, MA, United States
Job Details Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and prod
Job Source: BioSpace, Inc.Novartis Group Companies
Cambridge, MA, United States
Job Description Summary #LI-Hybrid Location: Cambridge, MA About the role: As a Therapeutic Area Biomarker Lead (TABL) for the renal portfolio, you will lead the renal disease area matrix teams of Biomarker Leads (leading at clinical project level) and subject matter experts and support key clinical projects as Biomarker Lead. Biomarkers are crit
Job Source: Novartis Group CompaniesWaltham, MA, United States
About us:
Ventus Therapeutics is a clinical-stage biopharmaceutical company deploying leading-edge structural biology and computational chemistry tools to create novel small molecule medicines for challenging targets in immunology, inflammation, and neurology.
Our proprietary drug discovery platform, ReSOLVE, gives us the ability to discover and develop medicines through unique insights into protein targets and to create dynamic blueprints that can guide the development of differentiated therapies at a fast pace. We aim to use the ReSOLVE platform to improve the way medicines are discovered and developed, with the ultimate goal of restoring the health of people facing serious illnesses.
Position overview:
Ventus is seeking an experienced translational scientist to lead the design and execution of biomarker strategies in support of our early and late-stage research programs. The candidate will be responsible for the development of translational biomarker approaches that measure target engagement, pharmacodynamics and disease pathology. As a strategic leader within a multidisciplinary team, the candidate will ensure that biomarker strategies align with the most current understanding of inflammatory disease biology and enable early clinical proof-of-concept. The candidate is expected to take a hands-on approach in the pre-clinical validation of such approaches using disease biospecimens. This role is a unique opportunity to work at the interface of discovery and development while championing biomarker-initiatives that have a direct impact on novel clinical study design.
Responsibilities:
Lead efforts to develop and implement translational biomarker strategies that assess proof of mechanism, establish early signs of efficacy and enable proof of concept studies
Partner with preclinical scientists to design and execute translational research to validate biomarker strategies
Collaborate with research and clinical teams to ensure the integration of biomarker discoveries into the design of early clinical studies
Oversee clinical validation of biomarker assays and collaborate with clinical pharmacology in the analysis of clinical biomarker studies
Contribute to discovery pipeline as a biology team representative
Requirements:
PhD with primary focus in Immunology with at least 8 years of pharmaceutical or biotechnology industry experience
Experience in small molecule drug discovery and program leadership
Experience in the identification and validation of pharmacodynamic and disease biomarkers, as well as their clinical implementation
Ability to drive and influence projects from discovery through early clinical development with a focus on the identification of indications and development of biomarker strategies that enable early proof-of-concept
Outstanding analytical, research and organizational skills
Strong interpersonal, influencing, and collaboration skills
Ability to prioritize, and be highly productive and flexible in a fast-paced, team-oriented environment
Ability to communicate scientific results to diverse audiences, in a clear and concise manner
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Email Alert for Principal Investigator, Translational Science (Biomarker Strategy) jobs in Waltham, MA, United States
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