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Revolution Medicines, Inc.
Redwood City, CA, United States
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment
Job Source: Revolution Medicines, Inc.IFF
Palo Alto
Associate Scientist Molecular Biology and Automation Apply now » Date:Jun 4, 2024 Location: Palo Alto, CA, US Company: IFF Family of Companies Job Description IFF is hiring an Associate Scientist to join our Molecular & Microbiology R&D team in Palo Alto, CA. At IFF Health & Biosciences, our R&D team develops microbial production strains (bacteria,
Job Source: IFFInternational Flavors & Fragrances
Palo Alto, CA, United States
Press Tab to Move to Skip to Content Link Select how often (in days) to receive an alert: Create Alert Select how often (in days) to receive an alert: Associate Scientist Molecular Biology and Automation IFF is hiring an Associate Scientist to join our Molecular & Microbiology R&D team in Palo Alto, CA. At IFF Health & Biosciences, our R&D team
Job Source: International Flavors & FragrancesIFF Family of Companies
Palo Alto, CA, United States
Job Description IFF is hiring an Associate Scientist to join our Molecular & Microbiology R&D team in Palo Alto, CA. At IFF Health & Biosciences, our R&D team develops microbial production strains (bacteria, yeast and filamentous fungi) and engineers enzymes for applications in the areas of food & beverages, biofuels, home & personal care, animal
Job Source: IFF Family of CompaniesRetro
Redwood City, CA, United States
Retro Biosciences is a fast-growing biopharma startup using high-throughput, high-dimensional approaches to develop therapies for diseases driven by the biology of aging. We are looking to expand our exceptional autophagy team at our Redwood City location. We have an open position for a Scientist/Sr. Scientist in Cell Biology. The candidate will b
Job Source: RetroKodiak Sciences Inc
Palo Alto, CA, United States
Kodiak Sciences is a fast-growing clinical-stage biotechnology company with a singular focus in ophthalmology. Our unique Antibody Biopolymer Conjugate (ABC) platform merges the fields of protein engineering and polymer chemistry and is at the core of our discovery engine. We are looking for a highly motivated, independent and skilled cell biologis
Job Source: Kodiak Sciences IncOrca Bio
Menlo Park, CA, United States
Over one million people in the world today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many patients, the transplant itself can prove fatal or lead to serious conditions, such as graft versus host disease. Orca Bio's investigational, high-precision cell therapies are designed to replac
Job Source: Orca BioStanford University
Palo Alto, CA, United States
The Quantitative Sciences Unit (QSU) is an interdisciplinary collaborative statistics unit in the Biomedical Informatics Research Division within the Department of Medicine at Stanford University. The mission of the QSU is to facilitate cutting-edge scientific studies initiated by Stanford investigators by providing expertise in biostatics and inf
Job Source: Stanford UniversityRedwood City, CA, United States
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are looking for a Senior Research Associate/Associate Scientist to join the Structural Biology (X-Ray Crystallography/CryoEM) team to support multiple oncology therapeutic programs. Working from the bench, they will apply their expertise in protein purification to form compound driven complexes, identify and optimize crystallization/CryoEM conditions with the aim of determining high resolution structural information to drive small molecule design.
Responsibilities:
Preparation of protein complexes for structural analysis (Crystallography/CryoEM)
Operate laboratory robotics for preparing and inspection of crystallization trials.
Communicate experimental design and results to cross-functional teams.
Manage and document experiments.
Required Skills, Experience and Education:
MSc. degree with 5+ years of experience or BSc. degree and a minimum of 8 years of experience
Experience with protein purification (AKTA) and/or biophysical characterization (Thermal melt, CD, SPR, anSEC).
Experience with protein-protein complexes including antibodies/Fabs, molecular glues, PROTACs, etc.
Experience with growing and harvesting protein crystals, preparing samples for CryoEM, prior use of structure determination/visualization software (CCP4, Phenix, Coot, PyMOL, Chimera), and/or CryoEM (Relion. CryoSPARC) are highly desirable skills.
Demonstrated ability to follow written protocols and document research progress.
Excellent written and verbal communication skills.
Conscientious team-player interested in a fast-paced biotech environment.
Demonstrated willingness to learn and improve processes.
Preferred Skills, Experience and Education:
Experience with biophysical characterization such as MS, SPR, NMR a plus.
Experience in protein expression including construct design and protein engineering.
The expected salary range for this role is $100,000 to $135,000. An individual's position within the range may be influenced by multiple factors, including skills and experience in role, overall performance, individual impact and contributions, tenure, and market dynamics. Base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
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Email Alert for Associate Scientist, Structural Biology jobs in Redwood City, CA, United States
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