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Director, Translational Sciences

, CA, United States

My client is at the forefront of developing innovative small molecule therapies aimed at transforming patient care. Their robust pipeline addresses unmet medical needs across various therapeutic areas, driven by a commitment to scientific excellence and innovation. They are seeking a highly skilled and experienced Director of Translational Sciences to join their dynamic team in Southern California.

Position Overview:

The Director of Translational Sciences will play a critical role in bridging preclinical research and clinical development. This leadership position requires a strategic thinker with a strong scientific background and experience in translational research, biomarker discovery, and clinical trial design. The ideal candidate will have a proven track record of advancing small molecule therapies from the lab to the clinic, ensuring the successful translation of our innovative therapies into clinical applications.

Key Responsibilities:

Lead and manage the Translational Sciences team, fostering a collaborative and innovative environment.

Develop and implement translational strategies to support the advancement of our small molecule pipeline.

Identify and validate biomarkers for patient selection, efficacy, and safety monitoring.

Design and oversee the execution of preclinical and early clinical studies to evaluate the pharmacodynamics, pharmacokinetics, and toxicology of small molecule candidates.

Collaborate with cross-functional teams, including Research, Clinical Development, Regulatory, and Commercial, to ensure seamless integration of translational efforts.

Serve as the translational science expert in external collaborations, partnerships, and regulatory interactions.

Analyze and interpret complex data sets, providing scientific insights and recommendations to guide decision-making.

Contribute to the preparation of regulatory submissions, scientific publications, and presentations.

Qualifications:

Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related field; M.D./Ph.D. or Pharm.D./Ph.D. preferred.

8+ years of experience in translational research within the biotech or pharmaceutical industry.

Demonstrated expertise in biomarker discovery, validation, and implementation.

Proven track record of successfully advancing small molecule therapies from preclinical research to clinical development.

Strong understanding of regulatory requirements and guidelines for translational studies.

Excellent leadership and team management skills, with the ability to inspire and mentor scientific staff.

I manage a range of other permanent and contract positions for a broad portfolio of clients (Biotech, CRO and Pharma). If the above role isn’t for you but you’d nevertheless like to discuss your options in the market, I’d welcome a confidential discussion by phone or email. Contact Charlie Pratummanee at +1 (619) 375 0895 or [email protected]

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