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Altos Labs
San Francisco, CA, United States
Our Mission To restore cell health and resilience through cellular rejuvenation programming to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos We believe tha
Job Source: Altos LabsUniversity of California - San Francisco
San Francisco, CA, United States
Application Window Open date: February 29, 2024 Next review date: Saturday, Mar 30, 2024 at 11:59pm (Pacific Time) Apply by this date to ensure full consideration by the committee. Final date: Friday, Aug 29, 2025 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date
Job Source: University of California - San FranciscoBridgeBio Pharma, Inc.
San Francisco, CA, United States
About BridgeBio BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medi
Job Source: BridgeBio Pharma, Inc.BridgeBio Pharma
San Francisco, CA, United States
About BridgeBio BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful med
Job Source: BridgeBio Pharma4D Molecular Therapeutics
Emeryville, CA, United States
Attention recruitment agencies: All agency inquiries are vetted through 4DMT's internal Talent Acquisition team. No unsolicited resumes will be accepted. Agencies must be expressly engaged by the 4DMT Talent Acquisition team on any requisition. Agencies reaching out directly to hiring managers will not be tolerated and doing so may impact your abi
Job Source: 4D Molecular TherapeuticsBioSpace, Inc.
Emeryville, CA, United States
Job Details Attention recruitment agencies: All agency inquiries are vetted through 4DMT's internal Talent Acquisition team. No unsolicited resumes will be accepted. Agencies must be expressly engaged by the 4DMT Talent Acquisition team on any requisition. Agencies reaching out directly to hiring managers will not be tolerated and doing so may i
Job Source: BioSpace, Inc.Mirum Pharmaceuticals, Inc.
Foster City, CA, United States
MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare liver diseases affecting children and adults. Propelled by our passion for patients and their families, we're focused on turning possibilities into realities. Using data and meaningful evidence, our goal is to transform scientific discoveri
Job Source: Mirum Pharmaceuticals, Inc.Mirum Pharmaceuticals, Inc.
Foster City, CA, United States
MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare liver diseases affecting children and adults. Propelled by our passion for patients and their families, we're focused on turning possibilities into realities. Using data and meaningful evidence, our goal is to transform scientific discoveri
Job Source: Mirum Pharmaceuticals, Inc.San Francisco, CA, United States
Location :
1800 Owens Street San Francisco , CA 94158 United States
Job Posted Date :
September 8, 2023
Full-time Positions
Population :
Life Sciences
Who You Are
The Computational Genetics team at BridgeBio plays a central role in establishing new drug development programs and supporting ongoing programs. The team is searching for a human geneticist to identify and validate therapeutic targets, understand the unmet need for various diseases, and, more generally, take a data-centric approach to drive drug development. You will apply your statistical/human genetics foundation to understand human genetic and clinical data from large biobanks and other databases in this role. Your strong biological intuition will guide you toward the right questions to ask and an appropriate analysis plan and help you communicate the results in a relevant and actionable way. To develop high-quality answers, you will be encouraged to be fearless and follow your nose to areas outside your immediate expertise. You will collaborate with a talented team of drug developers, including computational biologists, data engineers, clinicians, and bench scientists. Your insights will be shared with key external stakeholders and senior leadership and will ultimately guide the drug development efforts at BridgeBio. Finally, you will communicate relevant and novel findings to the broader scientific community through publication in scientific journals and presentations at external conferences.
Responsibilities
Apply biological and human genetics knowledge and intuition to identify essential and addressable questions/hypotheses to inform drug discovery and development
Design and implement analyses to produce interpretable, actionable results
Discuss project motivation, plan, and impacts with teammates, key external stakeholders, and senior leadership
Lead individual projects and collaborate with a diverse and talented team of drug developers
Stay at the leading edge of the field of human genetics, including new statistical methods, datasets, etc., and be able to discuss these new developments with both experts and non-experts
Attend and present at internal and external meetings; publish work in scientific journals
No matter your role at BridgeBio, successful team members are:
Patient Champions, who put patients first and uphold strict ethical standards
Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
Truth Seekers, who are detailed, rational, and humble problem solvers
Individuals Who Inspire Excellence in themselves and those around them
High-quality executors, who execute against goals and milestones with quality, precision, and speed
Job Requirements : Ph.D. in Human Genetics, Statistical Genetics, or related discipline with 0-2 years of industry or postdoctoral experience
Outstanding written and verbal communication skills in conveying analysis results to both experts and non-experts in the field
Extensive experience with Python and/or R with specific experience analyzing human genetics data (e.g., performing and interpreting GWASes/PheWASes, rare variant association tests, burden analyses, interpreting variant function and pathogenicity, etc.)
Experience in analyzing data from gnomAD, UK Biobank, All of Us, or similar cohorts
A strong history of completed scientific projects as evidenced by publications and presentations at conferences
A self-starter who loves to learn and will bring great energy to work each day
A passion for helping patients
How to Apply : BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 20+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.
Our focus on scientific excellence and rapid execution aim to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zurich, Switzerland, and are expanding across Europe.
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Email Alert for (Associate) Scientist, Statistical Geneticist/Human Geneticist jobs in San Francisco, CA, United States
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