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Vanda Pharmaceuticals
Boston, MA, United States
Vanda Pharmaceuticals (NASDAQ: VNDA) is a specialty pharmaceutical company focused on the development and commercialization of novel therapies to address high unmet medical needs and improve the lives of patients. We are looking for a Neuroscience Account Manager who wants to join an innovative and dynamic sales organization. We are seeking top tal
Job Source: Vanda Pharmaceuticalsmanifold.bio
Boston, MA, United States
Position We are seeking a hybrid scientist with a mix of wet and dry lab experience who is excited to go end-to-end designing, executing, and analyzing next-generation assay formats. With hybrid founders and a highly interdisciplinary team, we are strong believers in the synergy that comes from combining disciplines. You will design DNA libraries,
Job Source: manifold.bioHarvard Medical School and Brigham and Women's Hospital
Boston, MA, United States
Postdoc Fellow / Senior Scientist The Yakoub and Sulzer labs at Harvard Medical School-Brigham and Women’s Hospital and Columbia University are developing collaborative projects to explore transformative ideas focused on brain disease mechanisms and therapies and developing cutting-edge technologies for neuroscience. Example projects include: 1.
Job Source: Harvard Medical School and Brigham and Women's HospitalThe University of Texas MD Anderson Cancer Center
Boston, MA, United States
Job Title: Postdoc in Parkinson disease cell biology, Harvard Medical School / BWH Job Number: 76663 Location: Boston,US Job Description Postdoctoral Research Fellow position in Parkinson disease cell biology at Brigham and Women’s Hospital and Harvard Medical School, Boston A postdoctoral position is available under the mentorship of Gary H
Job Source: The University of Texas MD Anderson Cancer CenterDig Inn
Boston, MA, United States
CHEF-IN-TRAINING Up to $19 - $23/hr with tips* *Depending on experience Base wage before tips: $16 - 18 (+ $2-4/hour tips from a pool tips system) Interested in a 4-day workweek schedule while still getting full-time hours? This schedule is offered as an OPTIONAL BENEFIT for those interested & will include four swing shifts that will begin betwe
Job Source: Dig InnDIG Restaurant Teams
Boston
Job Description Job Description CHEF-IN-TRAINING Up to $19 - $23/hr with tips* *Depending on experience Base wage before tips: $16 - 18 (+ $2-4/hour tips from a pool tips system) Interested in a 4-day workweek schedule while still getting full-time hours? This schedule is offered as an OPTIONAL BENEFIT for those interested & will include four s
Job Source: DIG Restaurant TeamsBERKSHIRE HATHAWAY SPEC INS
Boston, MA, United States
A strategic and trusted insurance partner, Berkshire Hathaway Specialty Insurance (BHSI), provides a broad range of commercial property, casualty and specialty insurance coverages and outstanding service to customers and brokers around the world. Part of Berkshire Hathaway’s insurance operations, we bring our solutions to market with our stellar br
Job Source: BERKSHIRE HATHAWAY SPEC INSCerevel Therapeutics
Boston, MA, United States
Company Overview Cerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of
Job Source: Cerevel TherapeuticsBoston, MA, United States
Position
Manifold Bio is seeking an enthusiastic, highly creative neuroscience lead to expand our drug discovery efforts. You will work closely with the founders and R&D leadership to refine our neuroscience strategy and advance pipeline programs treating diseases of the CNS. The ideal candidate will have a strong scientific background and experience leading biologics programs in one or more CNS therapeutic areas (neurodegeneration, neuroinflammation, neuro-oncology, etc). This is a unique opportunity to work with world-class technologists innovating in cutting edge molecular biology and compute approaches to realize the potential of a novel protein engineering platform. You will lead early discovery projects that integrate our novel platform capabilities with both internal and external R&D resources. Together, we’ll continue to fundamentally change the current paradigm of drug development through the original vision of massively increasing the throughput of testing protein therapeutics.
Responsibilities
Guide company level neuroscience / CNS strategy
Evaluate new project/target opportunities and propose POC experiments
Leverage external resources and coordinate internal team members to lead projects from discovery to candidate selection
Coordinate with protein engineering on binder discovery and/or evaluate in-licensing opportunities, considering tradeoffs among target presentation and relation to disease biology
Design screening funnels that integrate our novel mDesign in vivo biologics design platform
Analyze and interpret data to enable decision making
Design development plans to early human PoC, including specifying DC nomination criteria
Required Qualifications
Biology Ph.D. or equivalent experience
Experience designing screening funnels leveraging both in vitro and in vivo assays with a focus on biologics ( 5-10 for Dir. level; 10+ for VP level)
Previous experience as a team lead or co-lead in an industry setting
Experience with hybrid drug discovery models blending external and internal R&D workflows
Highly independent and proactive, excellent communication and cross-functional team coordination skills
Preferred Qualifications
Experience with molecules that enhance BBB transcytosis (e.g. ‘shuttles’)
Experience and interest in assay development (in vitro/ex vivo/in vivo)
Experience with preclinical development and clinical trial planning
Why this might be a great role for you
You are eager to solve the challenge of CNS delivery of biologics
You love thinking about how to apply exciting new platforms
You are excited about starting drug programs from the very beginning
You want to join a small, agile, highly innovative team
We value different experiences and different ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.
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Neuroscience Biology Lead Boston, MA jobs in Boston, MA, United States
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