Research Associate, Sr. Research Associate
Boston, MA, United States
Seaport Therapeutics is seeking a Research Associate/Sr. Research Associate for a lab-based bioanalysis position with a focus on LC-MS. We are looking for a highly motivated individual who is looking to be a part of a multidisciplinary team and to gain experience in a startup environment. This position will contribute to advancing the pipeline of impactful candidates generated from our novel Glyph prodrug platform.
Some of the responsibilities will include:
Designing and executing in vitro experiments, using LC-MS, for the screening of lipid prodrugs to support preclinical discovery
Processing and analyzing in vivo samples (plasma, lymph fluid, etc.) to generate DMPK data for various prodrugs
Contributing to the development and optimization of LC-MS methods for both quantitative and qualitative analysis
Maintaining HPLC and MS instrumentation
Documenting all experiments using an electronic notebook and analyzing data for reports and regular internal presentations
Experience and Skills
BS (2-4 years of experience) or MS (0-2 years of experience) degree in pharmaceutical sciences, biochemistry, chemistry, or a related field
Hands-on experience operating and maintaining LC-MS/MS systems
Familiarity with various aspects of bioanalytical method development for LC-MS assays, including sample preparation techniques, chromatographic separation, and MRM method optimization
Strong attention to detail and the ability to troubleshoot technical issues independently
Proven ability to work collaboratively in a multidisciplinary team environment
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