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    Boston, MA, United States

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    Research Associate About the Opportunity This job description is intended to describe the general nature and level of work being performed by people assigned to this classification. It is not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of personnel so classified. JOB SUMMARY The Research A

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Research Associate, Sr. Research Associate

Boston, MA, United States

Seaport Therapeutics is seeking a Research Associate/Sr. Research Associate for a lab-based bioanalysis position with a focus on LC-MS. We are looking for a highly motivated individual who is looking to be a part of a multidisciplinary team and to gain experience in a startup environment. This position will contribute to advancing the pipeline of impactful candidates generated from our novel Glyph prodrug platform.

Some of the responsibilities will include:

Designing and executing in vitro experiments, using LC-MS, for the screening of lipid prodrugs to support preclinical discovery

Processing and analyzing in vivo samples (plasma, lymph fluid, etc.) to generate DMPK data for various prodrugs

Contributing to the development and optimization of LC-MS methods for both quantitative and qualitative analysis

Maintaining HPLC and MS instrumentation

Documenting all experiments using an electronic notebook and analyzing data for reports and regular internal presentations

Experience and Skills

BS (2-4 years of experience) or MS (0-2 years of experience) degree in pharmaceutical sciences, biochemistry, chemistry, or a related field

Hands-on experience operating and maintaining LC-MS/MS systems

Familiarity with various aspects of bioanalytical method development for LC-MS assays, including sample preparation techniques, chromatographic separation, and MRM method optimization

Strong attention to detail and the ability to troubleshoot technical issues independently

Proven ability to work collaboratively in a multidisciplinary team environment

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