NS Therapeutic Area Biomarker Lead (Associate Director)

Cambridge, MA, United States

Job Description Summary

About the role:

#LI-Hybrid

This position will be based on-site in Cambridge MA and will not be located remotely.

Over 800 biomarker discovery and development projects, across more than 100 clinical studies, which generate 20 petabytes of patient data! All waiting for you to unlock the next breakthrough in medicine.

Biomarkers are critical components of translational research, enabling robust therapeutic and mechanistic hypothesis testing in early clinical development, and as precision medicine enablers e.g. defining patient subpopulations, predicting patient responses, and use as diagnostics in later stages.

You will be leading a matrixed biomarker team of scientific experts to define the biomarker strategy and plan for a portfolio, defined by therapeutic mechanism or indication, from early to later stage clinical development. As a BioMarker Development project lead, you will be responsible to translate the preclinical discovery efforts into a clinical fit for purpose plan, oversee the integration into the clinical protocol and lead the review and discussions at the different teams and boards. Job Description

Key Responsibilities:

BMD strategic leader at project level and supports biomarker plan excellence with concise communication of the biomarkers in relation to compound/disease biology and impact.

The Biomarker Development project lead will be the BMD representative at DTB/DADB for the project/ portfolio.

Accountable for the biomarker strategy at a study level in coordination with the respective study lead, ensures alignment for projects within the disease area or across assets.

Representing BMD line functions in Therapeutic Area Line Function committees for clinical protocol development and operational milestone reviews.

Is responsible for the concept, endorsement, implementation, delivery and contextualization of the biomarker strategy and plan.

Reports to Therapeutic Area Biomarker Head (TABH) or Therapeutic Area Biomarker Lead (TABL) and cooperates closely to enable the project/study level biomarker strategy at concept and contextualizing stages.

Leads the biomarker subteam and the Development biomarker clinical subteam to align all key stakeholders on the biomarker strategy and plan at the project/study level and across their portfolio.

Aligns with the TABL/TABH to deliver on BMD TA strategy and initiatives.

Aligns with TABL for the attendance and representation for project teams at ePTs and GPTs.

Is an enterprise partner and strategic leader in the matrix environment, able to integrate and represent projects in the internal/external scientific discussions and initiatives.

Representative at key meetings including DADB and DTB for study level reviews and milestones.

Accountable for the biomarker strategy for their respective disease area or project

May act as a Biomarker Lead at the study level.

Essential Requirements:

• MD, MD/PhD, or PhD degree required, plus additional PhD/postdoc or equivalent level research

• Scientific excellence, or clinical expertise in neuroscience diseases/biology, or BM expertise evidenced by previous role or contributions in Neuroscience

• Experience in industry (Pharma or Biotech) for at least 3-5 years.

• Understanding of integrating a variety of biomarker modalities, and experience interacting with the various stakeholders within the organisation to ensure timely execution of plans and feasibility of implementing the proposed strategies in the clinical studies.

• Proven success in leading matrix (global, cross functional) teams including well developed interpersonal, communication (oral and written) and influencing skills

• Creative and innovative leadership with a sharp and objective intellect, and experience in balancing big picture thinking with detailed analysis

• Demonstrated passion for science, seeking out new clinical discovery opportunities and early clinical study approaches and ability to leverage KOL’s in the field.

Benefits and Rewards:

Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Benefit Summary: The pay range for this position at commencement of employment is expected to be between $166,400 - $249,600/year however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings

Salary Range

$166,400.00 - $249,600.00 Skills Desired

Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills, Curiosity, Data, Data Analysis, Decision Making, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy- Leadership, Influence, Laboratory, Lifesciences, Machine Learning (Ml), Medical Research, Mentorship {+ 11 more}

#J-18808-Ljbffr