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VP, Quantitative Systems Pharmacology

Chicago, IL, United States

SimBioSys (http://www.simbiosys.com) is seeking an exceptionally talented scientific leader to work on one of the most important challenges in medicine - individualizing care in Cancer.

We are building the future of precision cancer care with a groundbreaking 4D Tumor Modeling Platform, TumorScope, enabling:

1) Individualized Treatment Planning in Clinics

2) Insights via Proprietary Simul-omics

3) Optimized Drug Development & Clinical Trials

We are seeking a R&D leader to spearhead the development and implementation of mathematical models of drug efficacy. These models will support the expansion of TumorScope to novel mechanisms of action utilized for individualized treatment planning.

The work will require the rare ability to distill complex mechanisms of action down to their simplest terms, cast them in mathematical form, and implement computational methods to model them. Above all, ideal candidates should be creative problem-solvers, with a willingness to try a range of approaches to tackle each new challenge.

Areas of interest should include pharmacokinetics/pharmacodynamics, biochemical kinetics, and cancer-immune cell interactions.

The position will require you to design and drive projects and work closely with team members and pharmaceutical developers to model their drugs using early efficacy data, and analyze results from SimBioSys' TumorScope platform to provide insights for clinical trial optimization.

Fostering your leadership, analytical, biological, and computational skills, this position will provide you real world experience solving problems, while allowing you to contribute to the fight against cancer.

Requirements and Qualifications

M.S. or Ph.D. degree in Physics, Biophysics, Computational Biology, Bio/biomedical engineering, Bioinformatics, or a related experience in drug modeling

Excellent mathematical skills

Background in PK/PD modeling

5+ Experience in Biopharma

Team Management

Strong computer skills

Proficient in Python and/or C++

Excellent written and verbal communication skills

Strong background in statistics

Ability to work independently and as part of a team to meet project goals

Understanding of biology is critical

Desired Qualifications

Background in medical image analysis

Background in ‘Omics (genomics, transcriptomics, etc.)

Experience in designing, developing, and implementing software

Knowledge of oncological physiology is a plus

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