Scientist, Analytical Chem Research

San Diego, CA, United States

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

What We Do:

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

Responsible for assigned small molecule purification and analysis studies, in support of discovery programs at Neurocrine Biosciences Inc. using, but not limited to, HPLC/SFC chromatography, method development/optimization, achiral and chiral small molecule analysis and purification, and instrument maintenance/ troubleshooting.

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Your Contributions (include, but are not limited to):

* Performs daily HPLC and SFC achiral small molecule purification and analysis

* Executes and/or optimizes HPLC/SFC methods for achiral/chiral small molecules; supports the development of chiral and achiral methodologies to purify small molecules using mass-directed HPLC and SFC technology

* Perform routine instrument maintenance, repair and may troubleshoot complex instrument issues.

* Operates liquid handling robotics

* Uses sample data to develop preliminary analysis and findings

* Support the development of presentations of laboratory studies/analysis and findings

* Regularly sets up laboratory for new and/or continued purification and analysis

* Other duties as assigned

Requirements:

* Bachelor's degree in Chemistry, Biochemistry or similar discipline and 2+ years of experience in pharmaceutical industry, specifically small molecule purification and analysis. Hands-on experiences with HPLC / SFC Chromatography and liquid robotics preferred. Experience with analytical method development and preparative chromatography for small molecule chiral and achiral pharmaceutical compounds. Experience in instrument maintenance and troubleshooting preferred OR

* MS degree in Chemistry, Biochemistry or similar discipline and some industry experience as noted above OR

* PhD degree in Chemistry, Biochemistry or similar discipline and some industry or relevant experience a plus

* Recognizes fundamental anomalies in data points and identifies issues in experiments / processes

* Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals

* Strong knowledge of one scientific discipline

* Good knowledge of scientific principles, methods and techniques

* Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

* Ability to work as part of a team Strong computer skills

* Good problem-solving, analytical thinking skills

* Detail oriented

* Ability to meet deadlines

* Good project management skills

* Strong communication skills, ability to work independently, and creative approaches to problem solve, are essential in performing daily tasks and responsibilities

* Ability to identify complex problems and solves routine problems

* Ability to work under various timelines, while maintaining quality of work

* Working knowledge of HPLC/SFC chromatography. Analytical and preparative focus with this technology is required

* Continuous drive to increase lab productivity and throughput through scientific creativity

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

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