Process Development Scientist
Burlington, MA, United States
Garuda Therapeutics, a biotechnology company focused on developing off-the-shelf human hematopoietic stem cell-based cellular therapies, is seeking a highly motivated associate / senior associate to join its growing team. The full-time role will be a key member of the process development team, focusing on scaling up pluripotent stem cell expansion and differentiation in bioreactors, as well as implementing closed-system cell processors (e.g., cell washers, magnetic separation instruments, etc.) into a clinical manufacturing process. Under the supervision of the Director of CMC Strategy and Product Development and working closely within the R&D Department, the ideal candidate will be responsible for the day-to-day execution of projects relevant to the corefocus of the Garuda Tx. The position will be located in either Burlington, MA orCambridge, MA.
Key Responsibilities Include:
Culturing human pluripotent stem cells in various conditions, aiming to scale up expansion and differentiation
Implementation of closed-system cell processing systems
Designing and executing well-controlled in vitro experiments to demonstrate technological feasibility and improvements for characterization of cell product and/or achieve proof-of-concept in animal models
Collaborating internally with Garuda team, train colleagues in new techniques and maintain relationships with external scientific partners
Required Qualifications:
PhD with 1-3+ years, MS with 5-7+ years, or BS with 7+ years of related experience
Experience with cell culture in bioreactors and closed-system cell processing systems
Demonstrated excellence in planning, executing, and analyzing experiments
Critical thinking and independence, ability to troubleshoot, solve difficult problems, and develop process improvements
Attention to detail and careful record-keeping
Excellent organizational skills and ability to manage multiple projects
Excellent oral and written communication skills, able to write technical reports and protocols
Flexible team player excited to collaborate with internal and external partners
Highly self-motivated and flexibility in working schedule to accommodate weekend work if necessary
Preferred Qualifications:
Experience with human pluripotent stem cell culture
Experience with DOE and JMP
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