Solution Architect

Cambridge, MA, United States

Bicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating BT8009, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.

Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA.

Culture is key and all Bicycle employees actively embrace and role model our company values:

We are Adventurous . We believe it’s the way to deliver extraordinary results for our patients.

We are Dedicated to our Mission . You can’t change the world if you don’t have determination.

We are One Team . We only succeed when we work together.

Job Description As our team expands, we have created an exciting new opportunity for a Principal Solutions Architect at Bicycle Therapeutics’ offices at Granta Park, Cambridge.

We are looking for a proactive, highly motivated and ambitious Solutions Architect, with significant experience in taking proven web applications / platforms and driving their adoption within a business. We’re specifically looking for someone who has experience in developing Smartsheets based applications, with knowledge of Confluence / Jira.

You are someone who wants to challenge their skills, is a self-starter, is comfortable at working independently as well as across functions in the UK & US, and is motivated to make a difference by guiding staff to make business critical decisions. Our function’s core principle is to do the hard work to make things simpler for our users.

The goal of this role is to drive the adoption, and support the use of Smartsheets and other applications throughout Bicycle where automation and process enhancement can be made – making use of the power of Smartsheets as a unifying platform, and ensuring best practices are implemented. This includes lifting and optimizing current Microsoft Excel and/or Project workflows. A large part of this job will be to collaborate with stakeholders to deliver solutions that will allow all departments to explore data visually, and make data-driven decisions. Ultimately you will help to drive the next growth cycle at Bicycle.

Key responsibilities:

Work closely with the VP of Technology, Associate Director Technical Architect and IT Manager to help create and develop the technical vision and roadmap for Bicycle.

Drive the adoption of Smartsheets and Confluence across the business, identifying key opportunities and working to develop the requirements and then either developing them in-house, or working with vendors or third-parties to implement.

Drive the implementation of best practises for administering and maintaining these services.

Outside of these two main applications, you will help identify new platforms, apps and services to support all departments in Bicycle.

In certain scenarios, you may be leading the requirements of developing in-house solutions, and then working with the wider technology teams to bring prototypes into production.

Bringtogether web apps and developworkflows to minimize the number of manual steps in any process.

Upskilling and training relevant users in new solutions.

Help support all teams and departments to integrate solutions and platforms, and support their development so it aligns with overall Technology goals.

Be aware of the latest developments, standards and trends in solutions and opportunities to test and deploy at Bicycle.

Help support the delivery of solutions in alignment with our ISO 27001 certification.

Qualifications Demonstrable experiencein Smartsheets functions (control center, workspaces, power apps, sheets, reports, dashboards, etc.).

Experience in developing and implementing best practices with Confluence / Jira Cloud.

Experience in implementing tools and processes for automating deployment of services, and ensuring best practices are implemented.

Willingness to learn new software solutions and adapt to changing priorities

Methodical working practices and ability to translate user requirements into a technical specification

Understanding of cloud web apps, including those in the Microsoft 365 stack.

Ability to plan projects, realize attainable goals and drive work streams to completion.

Identifying opportunities for process improvements across Bicycle.

Excellent documentation and writing skills to maintain records of projects, processes and manuals.

Scripting experience (Python, R as a preference).

Experience with modern API’s.

Experience of working in the life sciences.

Awareness of Cybersecurity standards and best practices.

Additional Information State-of-the-art campus environmentwith on campus restaurant and Montessori nursery

Flexible working environment

Competitive reward including annual company bonus

28 days annual leave in addition to bank holidays+ option to buy up to 5 additional days annually

Employer contribution to pension (employee does not have to contribute)

Life assurance cover 4x basic salary

Private Medical Insurance, including optical and dental cover

Enhanced parental leave policies

Group income protection

Employee assistance program

Health Cash Plan

Access to company subsidized gym membership

Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Cycle to work scheme

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.

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