Senior Clinical Research Associate-LNP
Waltham, MA, United States
Research Associate II (Scientific)
Waltham, MA
5 Months contract
Pay Rate: $40-57/hr on w2
Pls read the job description before applying!
Open to candidates willing to relocate at their own expense Extension TBD Fully onsite Free parking Must Have: • 3+ years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization is a must • Direct experience with messenger RNA encapsulation/quantification/characterization/handling is required • Understanding and success in implementation of RNA-related analytics (Ribogreen, gel electrophoresis, capillary electrophoresis, etc.) is required Nice to Have: • Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred • Gene Therapy and or proficiency in the above • Masters degree is a plus. PHD will be over qualified for the role.
Fully Onsite
We are seeking a highly motivated and scientifically rigorous individual to join the Delivery and formulation development team. The position will focus on developing novel lipid nanoparticle (LNP) formulations for mRNA delivery.
Responsibilities
1. Prepare formulations and perform characterization assays/data analysis with focus on in vivo studies, drug carrier design/development, assay development etc.
2. Support vaccine formulation development activities.
3. Contribute in the development & writing/reviewing analytical method protocols.
4. Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.
Qualifications
• B.S./M.S. in Biomedical Engg/Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry
• 3+ years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization is a must
• Direct experience with messenger RNA encapsulation/quantification/characterization/handling is required
• Understanding and success in implementation of RNA-related analytics (Ribogreen, gel electrophoresis, capillary electrophoresis, etc.) is required
• Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred
• Experience in developing LNP formulations for gene/cell immunotherapy would be advantageous
• Works collaboratively within group as well as within interdisciplinary teams
• Manages time effectively demonstrating ability to perform multiple projects at one time
• Desire to work in a fast-paced environment
• Excellent organizational and communication skills
• Strong analytical and problem-solving skills